Designed specifically for genetics applications, the CLiR 5400 delivers up to 2.0 LPM of Type I, 18.2 MΩ water quality on demand. The water is purified using a staged purification process which includes high-purity ion exchange resins to remove dissolved minerals, ultraviolet light for bacteria sterilization and TOC reduction, and ultrafiltration for pyrogen removal and nuclease free water. TOC levels are actively monitored via on screen display. As the water exits the system, a final filter removes particulates and bacteria to reach Type I water specifications. The CLiR 5400 meets the challenges of delivering consistent ultra-pure water for critical research and testing in the life sciences. For applications like PCR, DNA Sequencing, Gel preparation, and general molecular biology, the need for RNase-free water becomes a necessity. Conventional methods use Diethyl pyrocarbonate (DEPC) treatment to inactivate RNase enzymes. With the use of the CLiR 5400, those processes are eliminated and contamination is reduced with an on-demand, ultrafiltration process. [Cartridges and final filter sold separately.]